Think Out of the Box, Think Out of the Eye Reappraisal of HIV/AIDS Retinopathy

In 1981, acquired immunodeficiency was proposed denominator of a newly defined syndrome of diseases that were on the rise in promiscuous male homosexuals and intravenous drug users (1). The reference to acquired immunodeficiency syndrome (AIDS) as a new disease (2,3), instead of a new syndrome composed of known diseases, inspired a search for a single new pathogen (2). In 1983 Montaigner and coworkers (4) suggested that pathogen to be lymphadenopathyassociated virus [now termed human immunodeficiency virus(HIV)] and Gallo et al. (5) believed human T-cell leukemia virus (HTLV) infection to be the cause of AIDS.